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DIAGNOSTIC TESTING



CHOLESTEROL DEFINITIONS


Total LDL
Cholesterol

LDL is the "bad" cholesterol and the primary cause of heart disease. It is the primary cholesterol target in heart disease risk management.

HDL Cholesterol

HDLis the protective or "good" cholesterol. Low levels of HDL are related to increased risk for coronary heart disease. Low HDL is an independent risk factor for heart disease.

VLDL Cholesterol

VLDL is the main carrier for Triglycerides and, if elevated, can be an independent risk factor for heart disease.

Total Cholesterol

Total Cholesterol is the amount of cholesterol circulating throughout your body.

Triglycerides

Triglycerides are energy-rich molecules needed for normal functions throughout the body. Elevated levels are associated with diabetes and cardiovascular disease.

Non-HDL
Cholesterol

Non-HDL Cholesterol is LDL + VLDL cholesterol. It has been shown to be a better predicator of heart disease risk than LDL alone.

Total apoB100

Total apoB100 combines all of the "bad" risk factors into a single value.

Lp(a)

The "Heart Attack" cholesterol, Lp(a), is a strongly inherited risk factor for heart disease. This does not respond to traditional LDL-lowering drugs.

IDL Cholesterol

IDL is a strongly inherited independent risk factor for heart disease and is elevated in patients with a family history of diabetes.

Real LDL
Cholesterol LDL-R

The Real LDL Cholesterol that circulates in your body. It is a component of Total LDL Cholesterol: Total LDL = Lp(a) + IDL + Real LDL.

LDL Cholesterol
Size Pattern

LDL exists in a range of sizes from small, dense "Pattern B" to large, buoyant "Pattern A." The smaller LDL cholesterol sizes are associated with an increased risk for heart disease. Small, dense LDL is prevalent in patients with insulin resistance or diabetes.

Metabolic
Syndrome

Metabolic Syndrome is characterized by the combination of several metabolic risk factors, including 1) elevated Triglycerides, 2) low HDL, and 3) small, dense Pattern B LDL that increase the overall risk for heart disease.

HDL2/HDL3 Cholesterol

HDL cholesterol sub-fractions are also used for risk prediction. HDL2 is large and buoyant and the most protective form of HDL cholesterol. Low HDL2 is a risk factor for heart disease in patients with normal LDL levels. HDL3 is small and dense and the least protective form of HDL.

Total apoAI

Total apoAI combines all of the "good" particles that are heart protective into a single value.

apoB100/apoAI
Ratio

The apoB/apoAI ratio is a measure of heart disease risk and in some studies has been shown to be the best predicator of risk. In general, the lower apoB/apoAI value, the lower your risk for heart disease.

VLDL3 Cholesterol

VLDL3 is the most dense VLDL sub-fraction and a greater risk factor for heart disease than both VLDL1 and VLDL2.


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